Mr. York has served as our Senior Vice President, Business Development & Commercial Strategy since December 2021. He joins Metacrine from PhaseBio, where he was Senior Vice President, Corporate Development and Alliance Management. At PhaseBio, Mr. York led a number of licensing and development deals and was the architect for bentracimab’s commercial strategy. Prior to PhaseBio, he served as Vice President, Global Business Development and Alliance Management at Orexigen Therapeutics, Inc., where he led global business development activities to license Orexigen assets and manage alliance partners. Before Orexigen, Michael was President and Chief Executive Officer of Senté Labs, Inc., a privately held company recognized as a leader in medical skincare products based on glycoproteins. Earlier in his career, Mr. York held roles of increasing responsibility at Amylin Pharmaceuticals, Santarus, Inc., Amgen, AstraZeneca and Merck & Co., Inc. He received an MBA from the University of Redlands and a B.A. in public administration and economics from San Diego State University.

Ms. Lowry joins Metacrine from Arena Pharmaceuticals, Inc. where she served as head of global HR operations & total rewards. Prior to Arena, she was head of global HR operations & total rewards at ACADIA Pharmaceuticals, and before that, head of global rewards & HR operations at Ultragenyx Pharmaceuticals, Inc. From 2014 to 2017 she took a sabbatical to train full-time to qualify for the Olympic trials in the marathon and obtain her M.S. in business and corporate law from the University of San Diego School of Law. Prior to that, Ms. Lowry was senior director, global total rewards & HR operations at ResMed Inc., and before that, director, human resources, global total rewards, talent acquisition & HRIS at Encore Capital Group, Inc. She began her career in HR as a consultant with Arthur Andersen and Ernst & Young. Ms. Lowry received her B.A. in Spanish language and literature from the University of Virginia.